葡萄胎组织MMPs与TIMPs表达及意义(3)

2025-06-15

总之，本文通过比较各组中MMPs及TIMPs的mRNA表达水平显示，虽然在有恶变倾向的葡萄胎中的表达均略高于良性葡萄胎和正常绒毛，但差异无显著性；而MMP9/TIMP1比值在葡萄胎恶变组中的表达高于正常绒毛组和葡萄胎未恶变组,因此认为MMP9/TIMP1比值可望作为判断葡萄胎预后的一项参考指标，特别是对葡萄胎有恶变倾向的病人进行预防性化疗可提供理论依据。

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